Imugex

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Categories: Biochemicals / Biochemicals

Storage			-20°C
Other names
Grade			Purified
Purity			Purified, dialyzed to remove any free 4-HNE.
Form			Supplied as a liquid in tris-buffered saline, pH 7.4, 0.01% benzethonium chloride.
Reactivity life			12 months
Note			For reserch purpose only
Description			HNE is a major product of endogenous lipid peroxidation. The w-6-family (linoleic and arachidonic acids) of polyunsaturated fatty acids may produce HNE as a result of free radical attack. HNE is a highly reactive compound and it can react with several functional groups on biological material, particularly sulfydryl groups to form thioester adduct and then hemiacetals. HNE may also react with histidine and lysine residues of proteins to form stable Michael addition-type of adducts. HNE-modified proteins may display an altered biological functions. Antibodies to HNE will help to visualize the HNE-adducts. Source: 4-Hydroxynonenal (BSA). Applications: Suitable for use in ELISA. Other applications not tested Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.