Neuropeptide Y Receptor, Type 4, Control Peptide (NPY 4R)

Catalog No : USB-N2176-65B
417.25€
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Product name Neuropeptide Y Receptor, Type 4, Control Peptide (NPY 4R)
Catalog No USB-N2176-65B
Supplier’s Catalog No N2176-65B
Supplier US Biologicals
Source antigen
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -20°C
Other names
Grade Purified
Purity Purified
Form Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
Reactivity life 12 months
Note For reserch purpose only
Purity Purified
Description Neuropeptide Y (NPY), a neuropeptide colocalized and abundantly released with the neurotransmitter norepinephrine in nervous system, synthesized by postnatal olfactory epithelium of sustentacular cells. It promotes the proliferation of postnatal neuronal precursor cells and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. NPY a 97aa peptide in mouse, human (chr 7p15.1) and 98aa in rat has a mol. wt of 11kD. NPY shows sequence homology to Peptide YY (PYY) and over 50% homology in amino acid and nucleotide sequence to Pancreatic Polypeptide (PNP or PPY), all of these homologous peptides has a 36aa mature peptide characterized by a hairpin loop. NPY4R/ PPYR1, a 375aa protein in mouse and human (Chr 10q11.2) is a receptor for NPY and PYY with high affinity to PPY. Highest levels of expression are found in Brain, Coronary artery and Ileum. Source: 15aa peptide from mouse NPY4R (1) Location: ~C-terminus, Cytoplasmic domain Species Sequence Homology: Rat-92%; Human, 86%; Chicken-64%. Applications: Suitable for use in ELISA as a control peptide for N2176-65. Other applications not tested. Recommended Dilution: ELISA: Coat ELISA plates at 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.