Abl Kinase Substrate (Abltide)
Catalog No : USB-A0007-07A
564.38€
0.00€
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| Product name | Abl Kinase Substrate (Abltide) | ||
|---|---|---|---|
| Catalog No | USB-A0007-07A | ||
| Supplier’s Catalog No | A0007-07A | ||
| Supplier | US Biologicals | ||
| Source antigen | Synthetic peptide | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Purified | ||
| Purity | 95+% HPLC, Mass Spec | ||
| Form | Supplied as a white to off-white lyophilized powder. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | 95+% HPLC, Mass Spec | ||
| Description | Synthetic linear peptide (EAIYAAPFAKKK)(K); substrate for Abl kinase. Abl Protein Tyrosine Kinase (AbI) is a truncated form of the v-AbI Protein Tyrosine Kinase, a partner in the Gag-Abl fusion protein of the Abelson murine leukemia virus. Abl contains 407 amino acids (residues 237-643 of the p120-gag-abl polyprotein) which include the kinase catalytic domain, SH2 domain on the N-terminus and the I237M mutation. Abl is identical to the normal c-Abl. Abl is autophosphorylated on tyrosine(s). Applications: Suitable for use in Kinase assay. Other applications not tested. Recommended Dilution: Kinase Assay: This lot at 50uM, was successfully phosphorylated using Abl, active. Assay background was subtracted from the actual counts. Representative results from a previous lot are shown at right. This peptide may also be used as a substrate for Abl (T315I), active and Abl, active, mouse. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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