Imugex

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Categories: Peptides & Proteins / Proteins

Product name			Stichodactyla Helianthus Neurotoxin [Gln9] (ShK)
Catalog No			USB-S7973-56F
Supplier’s Catalog No			S7973-56F
Supplier			US Biologicals
Source antigen			Synthetic
Reactivity
Cross reactivity
Applications
Molecular weight			4060.81

Storage			-20°C
Other names
Grade			Highly Purified
Purity			~95%. Purified by HPLC.
Form			Supplied as a lyophilized powder.
Reactivity life			12 months
Note			For reserch purpose only
Purity			~95%. Purified by HPLC.
Description			A peptide isolated from the Caribbean Sea anemone, Stichodactyla heliantus. The 35 amino acid residue peptide is the most potent inhibitor of Kv1.1 and Kv1.3 potassium ion channels discovered to date. The peptide has been produced synthetically and its solution structure has been determined by NMR. Over 380 analogs have been synthesized to gain an understanding of how the peptide interacts with potassium ion channels and to improve its specificity for Kv1.3 potassium channels. AA Sequence (linear): Arg-Ser-Cys-Ile-Asp-Thr-Ile-Pro-Gln-Ser-Arg-Cys-Thr-Ala-Phe-Gln-Cys-Lys-His-Ser-Met-Lys-Tyr-Arg-Leu-Ser-Phe-Cys-Arg-Lys-Thr-Cys-Gly-Thr-Cys Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.