Endothelin 1 (human, porcine, canine, rat, mouse, bovine)

Catalog No : USB-E3098-30K
529.90€
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Product name Endothelin 1 (human, porcine, canine, rat, mouse, bovine)
Catalog No USB-E3098-30K
Supplier’s Catalog No E3098-30K
Supplier US Biologicals
Source antigen Synthetic
Reactivity
Cross reactivity Bovine, Cat, Human, Mouse, Porcine, Rat
Applications
Molecular weight 2495.95
Storage -20°C
Other names
Grade Highly Purified
Purity ~95%. Purified by HPLC.
Form Supplied as a lyophilized powder.
Reactivity life 12 months
Note For reserch purpose only
Purity ~95%. Purified by HPLC.
Description Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms, ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart and liver. Amino Acid Sequence (linear): Cys-Ser-Cys-Ser-Ser-Leu-Met-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.