Osteoprotegerin, Recombinant, Human, His-Tag, aa201-401 (OPG)
Catalog No : USB-299495
419.55€
0.00€
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| Product name | Osteoprotegerin, Recombinant, Human, His-Tag, aa201-401 (OPG) | ||
|---|---|---|---|
| Catalog No | USB-299495 | ||
| Supplier’s Catalog No | 299495 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 31 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Purified | ||
| Purity | ~80% (RP-HPLC, SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder in PBS, 0.1% SDS, 1mM DTT. Reconstitute with sterile ddH2O. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~80% (RP-HPLC, SDS-PAGE) | ||
| Description | Osteoprotegerin, which is a member of the tumor necrosis factor receptor superfamily and is involved in the regulation of bone metabolism. OPG and its ligand (OPGL) are cytokines regulating osteoclasto-genesis. OPGL binds to receptors on the surface of preosteoclasts and stimulates their differentiation into active osteoclasts. This leads to osteoresorption. OPG inhibits this osteoclasto-genesis (OPG is secreted by osteoblasts, and binds to OPGL, thus inhibiting maturation of osteoclasts and osteoresorption). The degree and activity of osteoresorption depend mainly on the balance between OPG and its ligand (OPGL); factors increasing OPGL expression mostly reduce OPG expression and vice versa. Source: Recombinant protein corresponding to human OPG, fused to His-tag, expressed in E. coli. Molecular Weight: ~31kD Applications: Suitable for use in Western Blot and Antibody Production. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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