Imugex

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Categories: Peptides & Proteins / Proteins

Product name			Osteoprotegerin, Recombinant, Human (OPG, MGC29565, Osteoclastogenesis Inhibitory Factor, OCIF, TR1, Tumor Necrosis Factor Receptor Superfamily Member 11B, TNFRSF11B)
Catalog No			USB-O8065-01H
Supplier’s Catalog No			O8065-01H
Supplier			US Biologicals
Source antigen			E. coli
Reactivity
Cross reactivity
Applications
Molecular weight

Storage			-20°C
Other names
Grade			Highly Purified
Purity			~98% (SDS-PAGE and HPLC). Endotoxin: ≤0.1ng/ug.
Form			Supplied as a lyophilized powder. Reconstitute in 5mM Tris, pH 7.5 to a concentration of 0.1-1mg/ml.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~98% (SDS-PAGE and HPLC). Endotoxin: ≤0.1ng/ug.
Description			Human OPG (Osteoprotegerin), also known as OCIF (Osteoclastogenesis inhibitory factor), is a member of the TNF receptor superfamily. Recombinant human OPG/OCIF specifically acts on bone tissues and increases bone mineral density and bone volume associated with a decrease of active osteoclast number. Recombinant human OPG is a 20kD protein, comprising of 174 amino acid residues. Recombinant Human Osteoprotegerin (OPG) expressed in E. coli. Biological Activity: Determined by its ability to neutralize the stimulation of U937 cells treated with 10ng/ml of sRANKL. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with 5mM Tris. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.