Osteoprotegerin, Recombinant, Human (OPG, Osteoclastogenesis Inhibitory Factor, OCIF)

Catalog No : USB-O8065-01A
570.13€
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Product name Osteoprotegerin, Recombinant, Human (OPG, Osteoclastogenesis Inhibitory Factor, OCIF)
Catalog No USB-O8065-01A
Supplier’s Catalog No O8065-01A
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 19.9
Storage -20°C
Other names
Grade Highly Purified
Purity ~98% (SDS-PAGE, HPLC)
Form Supplied as a lyophilized powder in 10mM Tris, pH 7.5, 75mM sodium chloride. Reconstitute with 5mM Tris, pH 7.5, to 0.1-1mg/ml.
Reactivity life 6 months
Note For reserch purpose only
Purity ~98% (SDS-PAGE, HPLC)
Description Human OPG (Osteoprotegerin, also know as OCIF (Osteoclastogenesis inhibitory factor), is a member of the TNF receptor superfamily. Recombinant human OPG/OCIF specifically acts on bone tissues and increases bone mineral density and bone volume associated with a decrease of active osteoclast number. Source: Recombinant protein corresponding to 175aa from human Osteoprotegerin expressed in E. coli. Molecular Weight: ~19.9kD Endotoxin: ≤ 0.1ng/ug Biological Activity: Determined by its ability to neutralize the stimulation of U937 cells treated with 10ng/ml of soluble RANKL. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.