FTO, Recombinant, Mouse, aa2-502, His-Tag (Fat Mass and Obesity-Associated Protein, FATSO)

Catalog No : USB-301215
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Product name FTO, Recombinant, Mouse, aa2-502, His-Tag (Fat Mass and Obesity-Associated Protein, FATSO)
Catalog No USB-301215
Supplier’s Catalog No 301215
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 55
Storage -20°C
Other names
Grade Highly Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in 55mM Tris-Cl, pH 8.2, 150mM sodium chloride.
Reactivity life 12 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol. Source: Recombinant protein corresponding to aa2-502 of mouse FTO, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~55kD Endotoxin: <1EU/ug (LAL method) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.