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Categories: Peptides & Proteins / Proteins

Product name			Nampt , Recombinant, Rat (Visfatin/PBEF, PBEF1, Pre-B Cell Colony Enhancing Factor 1, Nicotinamide Phosphoribosyltransferase)
Catalog No			USB-045054
Supplier’s Catalog No			045054
Supplier			US Biologicals
Source antigen			Recombinant, Rat, HEK 293 cells
Reactivity
Cross reactivity
Applications
Molecular weight			60

Storage			4°C/-20°C
Other names
Grade			Highly Purified
Purity			>90% (SDS-PAGE)
Form			Supplied as a 0.2um-filtered solution in PBS, pH 7.2.
Reactivity life			6 months
Note			For reserch purpose only
Purity			>90% (SDS-PAGE)
Description			Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kD adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. Sequence: Rat Nampt (visfatin/PBEF) (aa 1-491) is fused at the N-terminus to a FLAG®-tag. Storage and Stability: Short-term Storage: +4°C Long-term Storage: -20°C Working aliquots are stable for up to 3 months when stored at -20°C.