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Categories: Peptides & Proteins / Proteins

Product name			FTO, Recombinant, Mouse, His-Tag (Fat Mass and Obesity-associated Protein, FATSO)
Catalog No			USB-044836
Supplier’s Catalog No			044836
Supplier			US Biologicals
Source antigen			Recombinant, Mouse, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			55

Storage			-20°C
Other names
Grade			Purified
Purity			≥90% (SDS-PAGE)
Form			Supplied as a liquid from a 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, 150mM NaCl.
Reactivity life			6 months
Note			For reserch purpose only
Purity			≥90% (SDS-PAGE)
Description			FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse 'fused toes' mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol. Sequence: Mouse FTO (aa2-502) is fused at the N-terminus to a His-tag, expressed in E. coli. Endotoxin: <1EU/ug (LAL test; Lonza) Molecular Weight: ~55kD (SDS-PAGE) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.