Boc-Leu-Arg-Arg-AMC (Boc-LRR-AMC, Proteasome Substrate)
Catalog No : USB-226821
357.48€
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| Product name | Boc-Leu-Arg-Arg-AMC (Boc-LRR-AMC, Proteasome Substrate) | ||
|---|---|---|---|
| Catalog No | USB-226821 | ||
| Supplier’s Catalog No | 226821 | ||
| Supplier | US Biologicals | ||
| Source antigen | Synthetic | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 773.8365 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥98% | ||
| Form | Supplied as a solid lyophilized powder. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Description | Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. Substrate for the Kex2 endopeptidase from S. Cervisiae, which has substrate specificity toward the C-terminal side of LR, PR and RR sequences. Can be cleaved by Kallikrein 5 with a P1 site preference for basic residues (R and K). This substrate is useful for inhibitor screening and kinetic analysis. CAS Number: 109358-46-5 (free base) Source: Synthetic Excitation: Excitation: 380nm. Emission: 460nm. Use: Add from DMSO stock directly to in vitro or in vivo assay at desired concentration. Typical concentrations range from 10-100uM. Molecular Formula: C33H52N10O7 . HCl Molecular Weight: 773.8 . 36.5 Sequence: Boc-Leu-Arg-Arg-7-amido-4-methylcoumarin Solubility: 5% acetic acid Purity: ≥98% Appearance: Supplied as a solid lyophilized powder. Storage and Stability: Stable for at least 1 year after receipt when stored at -20°C. | ||
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