Tissue Inhibitor of Metalloproteinases 1, Recombinant, Human (TIMP1, TIMP-1, TIMP, Collagenase Inhibitor, CLGI, Erythroid-potentiating Activity, EPA, Fibroblast Collagenase Inhibitor, Metalloproteinase Inhibitor 1)

Catalog No : USB-T5580-16B
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Product name Tissue Inhibitor of Metalloproteinases 1, Recombinant, Human (TIMP1, TIMP-1, TIMP, Collagenase Inhibitor, CLGI, Erythroid-potentiating Activity, EPA, Fibroblast Collagenase Inhibitor, Metalloproteinase Inhibitor 1)
Catalog No USB-T5580-16B
Supplier’s Catalog No T5580-16B
Supplier US Biologicals
Source antigen Recombinant, Sf9 cells
Reactivity
Cross reactivity
Applications
Molecular weight 28
Storage -70°C
Other names
Grade Highly Purified
Purity ~92% (SDS-PAGE)
Form Supplied as a liquid in 50mM Tris-HCl, pH 7.0, 200mM sodium chloride, 5mM calcium chloride, 1uM zinc chloride, 0.05% Brij 35, 0.05% sodium azide.
Reactivity life 6 months
Note For reserch purpose only
Purity ~92% (SDS-PAGE)
Description The tissue inhibitor of metalloproteinases (TIMP-1) is a glycoprotein with a molecular mass of about 28kD. The secreted protein consists of 184aa, six disuilfide bonds and two glycosylation sites containing N-linked oligosaccharides. TIMP-1 specifically inhibits the extracellular-matrix-egradingmetalloproteinases such as collagenase, gelatinase and stromelysin. It has no activity on mammalian membrane metallo-proteinases, procollagen peptidase, or on bacterial metalloproteinases such as thermolysin. Source: Recombinant corresponding to human TIMP-1 expressed in Sf9 cells. Molecular Weight: ~28kD Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.