Lrpap1, Recombinant, Mouse, aa29-360, His-Tag (Alpha-2-macroglobulin receptor-associated protein)

Catalog No : USB-350043
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Product name Lrpap1, Recombinant, Mouse, aa29-360, His-Tag (Alpha-2-macroglobulin receptor-associated protein)
Catalog No USB-350043
Supplier’s Catalog No 350043
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 41.4
Storage -20°C
Other names
Grade Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description Lrpap1 also known as Alpha-2-macroglobulin receptor-associated protein. The alpha-2- macroglobulin receptor-associated protein (RAP) is a glycoprotein that binds to the alpha-2- macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. Lrpap1 acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. Lrpap1 may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II. Source: Recombinant protein corresponding to aa29-360 of human Lrpap1, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~41.4kD AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSQPIAGHG GKYSREKNEP EMAAKRESGE EFRMEKLNQL WEKAKRLHLS PVRLAELHSD LKIQERDELN WKKLKVEGLD KDGEKEAKLI HNLNVILARY GLDGRKDAQM VHSNALNEDT QDELGDPRLE KLWHKAKTSG KFSSEELDKL WREFLHYKEK IQEYNVLLDT LSRAEEGYEN LLSPSDMAHI KSDTLISKHS ELKDRLRSIN QGLDRLRKVS HQGYGSTTEF EEPRVIDLWD LAQSANFTEK ELESFREELK HFEAKIEKHN HYQKQLEISH QKLKHVESIG DPEHISRNKE KYVLLEEKTK ELGYKVKKHL QDLSSRVSRA RHNEL Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.