Clusterin, Recombinant, Mouse, aa22-448, His-Tag (TRPM-2, Apolipoprotein J, APO-J, ApoJ, CLI, CLU, SGP-2, AAG4, KUB1, SGP2, SP-40, TRPM2)
Catalog No : USB-301194
513.81€
0.00€
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| Product name | Clusterin, Recombinant, Mouse, aa22-448, His-Tag (TRPM-2, Apolipoprotein J, APO-J, ApoJ, CLI, CLU, SGP-2, AAG4, KUB1, SGP2, SP-40, TRPM2) | ||
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| Catalog No | USB-301194 | ||
| Supplier’s Catalog No | 301194 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 45 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~90% (SDS-PAGE) | ||
| Form | Supplied as a liquid in 55mM Tris-Cl, pH 8.2, 150mM sodium chloride. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~90% (SDS-PAGE) | ||
| Description | Native Apolipoprotein J (ApoJ), also named Clusterin, is a heavily glycosylated, 75-80kD disulfide-linked heterodimeric protein. Despite being cloned since 1989, no genuine function has been attributed to ApoJ so far. The protein has been reportedly implicated in several diverse physiological processes such as sperm maturation, lipid transportation, complement inhibition, tissue remodeling, membrane recycling, cell-cell and cell-substratum interactions, stabilization of stressed proteins in a folding-competent state and promotion or inhibition of apoptosis. ApoJ gene is differentially regulated by cytokines, growth factors and stress-inducing agents. Clusterin is up- or down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others. Source: Recombinant protein corresponding to aa22-448 of mouse ApoJ/Clusterin, fused to His-tag at C-terminal expressed in E. coli. Molecular Weight: ~45kD Endotoxin: <1EU/ug (LAL method) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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