Apolipoprotein A-1, Recombinant, Human (ApoA-1, HDL, Cholesterol, LCAT)
Catalog No : USB-219430
483.92€
0.00€
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| Product name | Apolipoprotein A-1, Recombinant, Human (ApoA-1, HDL, Cholesterol, LCAT) | ||
|---|---|---|---|
| Catalog No | USB-219430 | ||
| Supplier’s Catalog No | 219430 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 28.2 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~97% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder. No preservative added. Reconstitute with sterile ddH2O to 0.1-1mg/ml. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~97% (SDS-PAGE) | ||
| Description | ApoA-I is a 29kD protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA-I, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis. For this reason HDL is also known as the “good cholesterol.” The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases. Source: Recombinant protein corresponding to 244aa residues from human Apolipoprotein A-1, expressed in E. coli. Molecular Weight: ~28.2kD Biological Activity: Test in process Endotoxin: <0.1ng/ug Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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