Apolipoprotein B, Human, Plasma
Catalog No : USB-A2255-10
483.92€
0.00€
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| Product name | Apolipoprotein B, Human, Plasma | ||
|---|---|---|---|
| Catalog No | USB-A2255-10 | ||
| Supplier’s Catalog No | A2255-10 | ||
| Supplier | US Biologicals | ||
| Source antigen | |||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 550 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | |||
| Purity | ~95% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder in 10mM Na deoxycholate, pH 10.0, 50mM Na2CO3, 50mM NaCI. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (SDS-PAGE) | ||
| Description | Apolipoprotein B is the dominant protein constituent of LDL. The concentration of Apo B in normal plasma is 90mg per 100ml. Apo B is thought to stabilize lipid emulsions, serve as a cofactor and modulator of enzymatic reactions, manage export of lipids out of cells and direct lipids to target organs. Apo B levels are positively correlated with the risk of coronary disease. Apo B levels may be a more sensitive predictor of cardiovascular risk than LDL levels and do not involve fasting for accurate measurement. Two forms of Apo B exist: Apo B-100 and Apo B-48. The first is found in VLDL and LDL and is produced by the liver. The second is found in chylomicrons and originates in the intestine. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. Source: Human plasma. Prepared from plasma shown to be non-reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA approved tests. Molecular Weight: ~550kD Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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