Ulex europaeus (UEA I)
Catalog No : USB-518854
397.71€
0.00€
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| Product name | Ulex europaeus (UEA I) | ||
|---|---|---|---|
| Catalog No | USB-518854 | ||
| Supplier’s Catalog No | 518854 | ||
| Supplier | US Biologicals | ||
| Source antigen | Gorse | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 63 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Affinity purified | ||
| Purity | Affinity purified | ||
| Form | Supplied as a lyophilized powder. | ||
| Reactivity life | 2 years | ||
| Note | For reserch purpose only | ||
| Purity | Affinity purified | ||
| Description | ""Ulex europaeus agglutinin (UEA I) is affinity purified isolated from gorse seeds and separated from crude extract by affinity chromatography. It is consists of two subunits. The lectin is a glycoprotein that has no mitogenic activity to agglutinates type O erythrocytes, and of a lesser degree to individuals with A2 erythrocytes.UEA I reacts strongly with alpha(1,2) linked fucose residues but poorly or not at all with alpha(1,3) or alpha(1,6)-linked fucose. UEA I is unable to bind internal fucose structures and the presence of an internal alpha(1,3)-linked fucose on the H type 2 oligosaccharide decreases lectin affinity for this blood group antigen by 3-fold.UEA I has been used as a marker for vascular endothelium and used to identify endothelial cells of benign vascular lesions more specifically than antibodies Factor VII-related antigen. UEA I coated magnetic beads have been used to isolate endothelial cells associated with micro-vessels for subsequent cell culture. This lectin has also been used to differentiate between angiosarcomas and epithelial tumor. Source: Gorse Blood Specificity: O > A2 Sugar Specificity: alpha-Fucose Inhibitory Carbohydrate: L-Fucose Divalent Ions: Ca++, Mn++, Zn++ Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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