Styphnolobium japonicum (SJA) (Semi-Pure)
Catalog No : USB-518775
411.51€
0.00€
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| Product name | Styphnolobium japonicum (SJA) (Semi-Pure) | ||
|---|---|---|---|
| Catalog No | USB-518775 | ||
| Supplier’s Catalog No | 518775 | ||
| Supplier | US Biologicals | ||
| Source antigen | Japanese pagoda tree | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 133 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | |||
| Purity | Semi-Pure | ||
| Form | Supplied as a lyophilized powder. | ||
| Reactivity life | 2 years | ||
| Note | For reserch purpose only | ||
| Purity | Semi-Pure | ||
| Description | Styphnolobium japonicum agglutinin (SJA) is fractionated from Japanese pagoda tree seeds. It consists of two subunits. The subunits can be separated into two subfractions, a D-galactose/N-acetyl-D-galactosamine specific lectin (B-SJA-I) and a D-mannose/D-glucose specific lectin (B-SJA-II). SJA has an isoelectric point between pH 4.9 and pH 5.6 and a carbohydrate specificity towards βGalNAc. This lectin elutes with the sugar GalNAc.SJA agglutinates all blood group types but has greater affinity for A erythrocytes than of B types, than of O (-SA) types. Binding experiments of the lectin with frozen sections of human kidneys shows specific binding to the endothelia in specimens from blood groups B or AB, thus indicating a D-galactose/N-acetyl-D-galactosamine receptor specificity. SJA lacks mitogenic and immune-suppressive activity. Source: Japanese pagoda tree Blood Specificity: A > B > O (-SA) Sugar Specificity: beta-N-Acetylgalactosamine Inhibitory Carbohydrate: N-Acetylgalactosamine Divalent Ions: Ca++, Mn++ Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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