Imugex

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Categories: Peptides & Proteins / Proteins

Storage			-20°C
Other names
Grade			Affinity purified
Purity			Affinity purified
Form			Supplied as a lyophilized powder.
Reactivity life			2 years
Note			For reserch purpose only
Purity			Affinity purified
Description			Sambucus nigra Lectin (SNA/EBL I) is an isolectin isolated from elderberry bark and purified by affinity chromatography. SNA I belongs to the group of type 2 ribosome-inactivating proteins and is composed of an A-chain with enzymatic activity and a B-chain with carbohydrate-binding activity. It has specificity for alpha2,6-linked sialic acid residues, and elutes with the sugar lactose. SNA I can induce apoptosis through the caspase-dependent pathway at low concentrations. This effect depends on the carbohydrate binding of the B-chain and is independent from the catalytic activity of the A-chain. Source: Elderberry Blood Specificity: A > B > O Sugar Specificity: Sialic Acid Inhibitory Carbohydrate: Lactose > beta-Galactose Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.