Imugex

Shipping cost plus VAT not included , delivery in 7-14 business days

Categories: Peptides & Proteins / Proteins

Product name			Maclura pomifera (MPL/MPA) (Semi-Pure)
Catalog No			USB-518560
Supplier’s Catalog No			518560
Supplier			US Biologicals
Source antigen			Osage orange
Reactivity
Cross reactivity
Applications
Molecular weight			44

Storage			-20°C
Other names
Grade
Purity			Semi-Pure
Form			Supplied as a lyophilized powder.
Reactivity life			2 years
Note			For reserch purpose only
Purity			Semi-Pure
Description			Maclura pomifera agglutinin or lectin (MPA/MPL) is tetrameric plant protein purified by fractionation. MPA has a molecular weight of about 44,000 and consists of four subunits. It has an isoelectric point between pH 4.8 and pH 5.3, and blood group specificity towards A, B, and O (-SA). This lectin has a high affinity for tumor-associated T-antigen disaccharide (Galβ1,3GalNAcalpha; ) and many O-linked glycopeptide structures. The structure of Galβ1,3GalNAcalpha; occurs on the surface of tumor cells as a mucin-associated antigenic marker, termed as T-antigen. It is also the central element in O-linked glycopeptide structures on other mammalian glycoproteins. Source: Osage orange Blood Specificity: A, B, O (-SA) Sugar Specificity: Galbeta; 3GalNAc Inhibitory Carbohydrate: Galactose Divalent Ions: None Required Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.