Griffonia simplicifolia (GSL I)
Catalog No : USB-518399
390.82€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Product name | Griffonia simplicifolia (GSL I) | ||
|---|---|---|---|
| Catalog No | USB-518399 | ||
| Supplier’s Catalog No | 518399 | ||
| Supplier | US Biologicals | ||
| Source antigen | Bandeiraea | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 114 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Affinity purified | ||
| Purity | Affinity purified | ||
| Form | Supplied as a lyophilized powder. | ||
| Reactivity life | 2 years | ||
| Note | For reserch purpose only | ||
| Purity | Affinity purified | ||
| Description | Griffonia simplicifolia lectin (GSL I) is affinity purified from a woody climbing shrub native to Africa. GSL I is composed of two types of subunits A and B that combine to form tetrameric structures, resulting in five isolectins. This lectin has affinity for terminal alpha-D-galactosyl residues and terminal N-acetyl-alpha-D-galactosaminyl residues. The A-rich lectin preferentially agglutinates blood group A erythrocytes and thus appears to be specific for alpha-N-acetylgalactosamine residues, while the B-rich lectin preferentially agglutinates blood group B cells and is specific for alpha-galactose residues. This lectin shows specificity for blood group B greater than blood group A1. GSL I has been reported to bind several glycoproteins including laminin. Since some alpha-D-galactosyl residues are expressed in endothelial cells of mouse tissues, GSL I can present a highly specific surface of glycosylation pattern in these cells. Source: Bandeiraea Blood Specificity: B >> A1 Sugar Specificity: alpha-Galactose, alpha-N-Acetylgalactosamine Inhibitory Carbohydrate: Galactose, N-Acetylgalactosamine Divalent Ions: Ca++, Mn++ Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
Product Details
© 2020 Imugex All Rights Reserved