SIGLEC7, GST-Tag, Recombinant (p75, QA79, AIRM1, CD328, CDw328, D-siglec, SIGLEC-7, p75/AIRM1, SIGLEC7, Sialic Acid-Binding Ig-Like Lectin 7)
Catalog No : USB-500965
482.77€
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| Product name | SIGLEC7, GST-Tag, Recombinant (p75, QA79, AIRM1, CD328, CDw328, D-siglec, SIGLEC-7, p75/AIRM1, SIGLEC7, Sialic Acid-Binding Ig-Like Lectin 7) | ||
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| Catalog No | USB-500965 | ||
| Supplier’s Catalog No | 500965 | ||
| Supplier | US Biologicals | ||
| Source antigen | E. coli, Recombinant | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 38 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Lysate | ||
| Purity | Lysate | ||
| Form | Supplied as a lyophilized powder in Tris-HCl, pH 6.8, 0.2M DTT, 4% SDS, 0.2% bromophenol blue, 20% sucrose. Reconstitute with 200ul sterile dH2O. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | Lysate | ||
| Description | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro). Source: Partial length protein corresponding to of SIGLEC7, fused to GST-Tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Molecular Weight: ~38kD Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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