LGALS3, Recombinant, Mouse, aa1-264, His-Tag (Lectin Galactose binding soluble 3, CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2)

Catalog No : USB-351347
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Product name LGALS3, Recombinant, Mouse, aa1-264, His-Tag (Lectin Galactose binding soluble 3, CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2)
Catalog No USB-351347
Supplier’s Catalog No 351347
Supplier US Biologicals
Source antigen Recombinant, mouse from E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 29.8
Storage -20°C/-70°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.15M sodium chloride, 1mM DTT, 2mM EDTA, 50% glycerol.
Reactivity life 12 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description LGALS3, also known as galectin 3, is a member of the family of animal lectins, which selectively binds beta-galactoside residues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. LGALS3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins Source: Recombinant protein corresponding to aa1-264 from mouse LGALS3, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~29.8kD (287aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMADSFSL NDALAGSGNP NPQGYPGAWG NQPGAGGYPG AAYPGAYPGQ APPGAYPGQA PPGAYPGQAP PSAYPGPTAP GAYPGPTAPG AYPGSTAPGA FPGQPGAPGA YPSAPGGYPA AGPYGVPAGP LTVPYDLPLP GGVMPRMLIT IMGTVKPNAN RIVLDFRRGN DVAFHFNPRF NENNRRVIVC NTKQDNNWGK EERQSAFPFE SGKPFKIQVL VEADHFKVAV NDAHLLQYNH RMKNLREISQ LGISGDITLT SANHAMI Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.