LGALS3, Recombinant, Mouse, aa1-264, His-Tag (Galectin 2)

Catalog No : USB-351346
394.26€
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Product name LGALS3, Recombinant, Mouse, aa1-264, His-Tag (Galectin 2)
Catalog No USB-351346
Supplier’s Catalog No 351346
Supplier US Biologicals
Source antigen Recombinant, mouse from E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 17.3
Storage -20°C/-70°C
Other names
Grade Highly Purified
Purity ~95% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.1M sodium chloride, 1mM DTT, 10% glycerol.
Reactivity life 12 months
Note For reserch purpose only
Purity ~95% (SDS-PAGE)
Description Galectin 2, also known as Lgals2, belongs to the galectins family. Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Lgals2 is a monomeric or homodimeric prototype galectin that is expressed in hepatoma, stomach epithelial cells and in colorectal and neural tumors. It induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-a (LTA) with possible implications in risk of myocardial infarction. Human and mouse Lgals2 share approximately 65% amino acid sequence similarity. Source: Recombinant protein corresponding to aa1-264 from mouse Lgals2, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~17.3kD (153aa) Biological Activity: Measured by its agglutinate human red blood cells, the ED50 for this effect is ~20ug/ml. AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSEKFEV KDLNMKPGMS LKIKGKIHND VDRFLINLGQ GKETLNLHFN PRFDESTIVC NTSEGGRWGQ EQRENHMCFS PGSEVKITIT FQDKDFKVTL PDGHQLTFPN RLGHNQLHYL SMGGLQISSF KLE Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.