Galectin-1, active (LGALS1), Recombinant, Human
Catalog No : USB-348056
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| Product name | Galectin-1, active (LGALS1), Recombinant, Human | ||
|---|---|---|---|
| Catalog No | USB-348056 | ||
| Supplier’s Catalog No | 348056 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Human, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 14.6 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥95% as determined by SDS-PAGE and HPLC. | ||
| Form | Lyophilized from 0.2um filtered 20mM PBS, pH 7.4, 150mM NaCl | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥95% as determined by SDS-PAGE and HPLC. | ||
| Description | May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. {ECO:0000269|PubMed:14617626, ECO:0000269|PubMed:18796645, ECO:0000269|PubMed:19497882}. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human blood monocytes is in a concentration range of 1.0-10ng/ml. Sequence: ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPFQ PGSVAEVCIT FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFD Molecular Weight: 14.6kD PubMed ID: 2719964; 2910856; 2719646; 18824694; 1988031; 12761501; 15461802; 14702039; 10591208; 15489334; 3065332; 12665801; 3611046; 1386213; 2383549; 7501023; 10e369126; 10764829; 11146440; 14617626; 19497882; 19608861; 21269460; 22905912; 22223895; 22814378; 23131994; 24275569; 260910e39; 15476813; 18796645; 19128029 Gene Name: LGALS1 Swiss Prot: P09382 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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