Galectin-1, Recombinant, Human (Beta-galactoside-binding lectin L-14-I, Galaptin, 14kD lectin, S-LAC lectin-1)

Catalog No : USB-143336
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Product name Galectin-1, Recombinant, Human (Beta-galactoside-binding lectin L-14-I, Galaptin, 14kD lectin, S-LAC lectin-1)
Catalog No USB-143336
Supplier’s Catalog No 143336
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -20°C
Other names
Grade Highly Purified
Purity ≥98% by SDS-PAGE gel and HPLC analyses. Endotoxin: ≤0.1ng/ug (≤1EU/ug).
Form Supplied as a lyophilized powder from 10mM sodium phosphate, pH 7.5. Reconstitute with sterile dH2O to 0.1-1mg/ml.
Reactivity life 12 months
Note For reserch purpose only
Purity ≥98% by SDS-PAGE gel and HPLC analyses. Endotoxin: ≤0.1ng/ug (≤1EU/ug).
Description Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells.The Galectins are lectins that recognize and interact with beta-galactoside moieties.Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45.It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45.Recombinant human Galectin-1 is a 14.5kD protein containing 134 amino acid residues. Biological Activity: Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5ug/ml with a peak response obtained at 250ug/ml. AA Sequence: ACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD Quality Control: Verified by N-terminal and Mass Spectrometry analyses (when applicable). Protein Content: Verified by UV Spectroscopy and/or SDS-PAGE gel. Storage and Stability: Store lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.