Hirudin, active (HIRUD), Poecilobdella viridis, Recombinant
Catalog No : USB-348222
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| Product name | Hirudin, active (HIRUD), Poecilobdella viridis, Recombinant | ||
|---|---|---|---|
| Catalog No | USB-348222 | ||
| Supplier’s Catalog No | 348222 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Poecilobdella viridis, Yeast | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 6.7 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥96% as determined by SDS-PAGE and HPLC. | ||
| Form | Lyophilized from 0.2um filtered 20mM PBS, pH 7.4, 150mM NaCl | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥96% as determined by SDS-PAGE and HPLC. | ||
| Description | Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen. Recombinant Poecilobdella viridis, active (HIRUD) Biological Activity: The biological activity is determined by chromogenic assay, 1 unit is defined as the amount of Hirudin that neutralizes 1 unit of the WHO preparation 89/588 of thrombin. The specific activity is no less than 14,000 ATU/mg protein. Sequence: VVYTDCTESG QNLCLCEGSN VCGQGNKCIL GSDGEKNQCV TGEGTPGPQS HNDGDFEEPE EYL Molecular Weight: 6.7kD Swiss Prot: P84590 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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