HIV-1 p31, Integrase, Recombinant, GST-tag, aa9-289
Catalog No : USB-208999
417.25€
0.00€
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| Product name | HIV-1 p31, Integrase, Recombinant, GST-tag, aa9-289 | ||
|---|---|---|---|
| Catalog No | USB-208999 | ||
| Supplier’s Catalog No | 208999 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | Highly Purified (~95%) | ||
| Form | Supplied as a liquid in 25mM Tris-HCl, pH 8.0, 0.2% Triton-X, 1.5M urea, 50% glycerol. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | Highly Purified (~95%) | ||
| Description | Integrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell and is a key component in the pre-integration complex. HIV integrase contains 3 domains, an N-terminal HH-CC zinc finger domain which is partially responsible for multimerization, a central catalytic domain and a C-terminal domain. Both Central catalytic domain and C-terminal domains have been shown to bind both viral and cellular DNA. No crystal structure data exists with Integrase bound to its DNA substrates. HIV-1 integrase functions as a dimer or a tetramer. Additionally, several host cellular proteins interact with integrase and may facilitate the integration process. Source: Recombinant protein corresponding to a non-glycosylated polypeptide chain, containing the HIV-1 immunodominant regions from the p31 protein (intergrase), aa9-289, with a GST-tag at N-terminal, expressed in E. coli. Specificity: Immunoreactive with all sera of HIV-1 infected individuals. Applications: Suitable for use as an antigen in ELISA and Western Blot, excellent for early detection of HIV seroconvertors with minimal specificity problems. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | ||
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