Anti-HSPB1 Antibody

Catalog No : IGX-59453
282.00€
201.00€

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Description Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state (PMID:10383393, PMID:20178975). Plays a role in stress resistance and actin organization (PMID:19166925). Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins (PMID:23728742).
Other names Heat shock protein beta-1, HspB1, 28 kDa heat shock protein, Estrogen-regulated 24 kDa protein, Heat shock 27 kDa protein, HSP 27, Stress-responsive protein 27, SRP27, HSPB1, HSP27, HSP28
Cellular localization Cytoskeleton, Spindle, Nucleus, Cytoplasm
Research area Signal Transduction
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P04792
Product name Anti-HSPB1 Antibody
Catalog No IGX-59453
Supplier’s Catalog No IGX-59453
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, WB, IHC, IF, Flow cyto, IP; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000
Recommended dilutions WB: 1:500-1:5000, IHC: 1:50-1:200, IF: 1:20-1:200, IP: 1:200-1:1000
Molecular weight Predicted band size: 23 KDa Observed band size: 27 KDa
Conjugate Unconjugated
Immunogen A synthesized peptide derived from human HSPB1
Specificity This antibody detects total endogenous levels of HSPB1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Monoclonal
Isotype Rabbit IgG
Clone ID N/A
Concentration Concentration can vary between different batches.
Storage buffer Phosphate-buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Formulation Liquid
Purification Affinity Purified
Handling This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).