Anti-ITGB4 Antibody
Catalog No : IGX-50478
262.00€
188.00€
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| Description | Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PMID:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PMID:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PMID:28873464). | ||
|---|---|---|---|
| Other names | Integrin beta-4, GP150, CD antigen CD104, ITGB4 | ||
| Cellular localization | Plasma Membrane, Membrane, Single-Pass Type I Membrane, Lipid-Anchor, Hemidesmosome | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P16144 | ||
| Product name | Anti-ITGB4 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-50478 | ||
| Supplier’s Catalog No | IGX-50478 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Mouse | ||
| Applications | ELISA, WB, IHC, IF | ||
| Recommended dilutions | WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | Predicted band size: 203 KDa. Observed band size: 203 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Integrin beta-4 protein (1401-1533AA) | ||
| Specificity | ITGB4 antibody detects endogenous level of ITGB4 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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