Anti-FOXE3 Antibody
Catalog No : IGX-49742
262.00€
188.00€
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| Description | Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle (PMID:22527307, PMID:25504734). During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation . Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm . Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye (PMID:27218149). | ||
|---|---|---|---|
| Other names | Forkhead box protein E3, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8, FREAC-8, FOXE3, FKHL12 FREAC8 | ||
| Cellular localization | Nucleus | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q13461 | ||
| Product name | Anti-FOXE3 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-49742 | ||
| Supplier’s Catalog No | IGX-49742 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human, Rat, Mouse | ||
| Applications | ELISA, WB, IF | ||
| Recommended dilutions | WB: 1:500-1:5000, IF: 1:50-1:200 | ||
| Molecular weight | Predicted band size: 34 KDa. Observed band size: 34 KDa. | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Forkhead box protein E3 protein (4-74AA) | ||
| Specificity | FOXE3 antibody detects endogenous level of FOXE3 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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