Anti-KCNJ8 / Inward rectifier K channel Kir6.1 Antibody

Catalog No : IGX-45619
262.00€
188.00€

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Description This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium .
Other names ATP-sensitive inward rectifier potassium channel 8, Inward rectifier K,+, channel Kir6.1, Potassium channel, inwardly rectifying subfamily J member 8, uKATP-1, KCNJ8
Cellular localization Membrane, Multi-Pass Membrane
Research area
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q15842
Product name Anti-KCNJ8 / Inward rectifier K channel Kir6.1 Antibody
Catalog No IGX-45619
Supplier’s Catalog No IGX-45619
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:500-1:1000, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human ATP-sensitive inward rectifier potassium channel 8 protein (299-424AA)
Specificity KCNJ8 antibody detects endogenous level of KCNJ8 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).