Anti-SLC25A33 Antibody
Catalog No : IGX-44018
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria (PMID:25320081). Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism (PMID:25320081). Also transports guanine but not adenine (deoxy)nucleotides (PMID:25320081). Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate) (PMID:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration (PMID:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production (PMID:20453889, PMID:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation (PMID:14715278). | ||
|---|---|---|---|
| Other names | Solute carrier family 25 member 33, Bone marrow stromal cell mitochondrial carrier protein, BMSC-MCP, HuBMSC-MCP, Protein PNC1, SLC25A33 | ||
| Cellular localization | Mitochondrion Inner Membrane, Multi-Pass Membrane | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9BSK2 | ||
| Product name | Anti-SLC25A33 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-44018 | ||
| Supplier’s Catalog No | IGX-44018 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Solute carrier family 25 member 33 protein (66-120AA) | ||
| Specificity | SLC25A33 antibody detects endogenous level of SLC25A33 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
Product Details
© 2020 Imugex All Rights Reserved