Anti-DOK1 Antibody

Catalog No : IGX-43997
262.00€
188.00€

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Description DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
Other names Docking protein 1, Downstream of tyrosine kinase 1, p62,dok, pp62, DOK1
Cellular localization Cytoplasm, Nucleus, Perinuclear Region
Research area Cardiovascular
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q99704
Product name Anti-DOK1 Antibody
Catalog No IGX-43997
Supplier’s Catalog No IGX-43997
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:20-1:200, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Docking protein 1 protein (1-481AA)
Specificity DOK1 antibody detects endogenous level of DOK1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).