Anti-KCNIP4 Antibody

Catalog No : IGX-43915
262.00€
188.00€

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Description Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner (PMID:11847232, PMID:18957440, PMID:23576435). Modulates KCND3/Kv4.3 currents (PMID:23576435). Isoform 4 does not increase KCND2 expression at the cell membrane (PMID:18957440). Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane.
Other names Kv channel-interacting protein 4, KChIP4, A-type potassium channel modulatory protein 4, Calsenilin-like protein, Potassium channel-interacting protein 4, KCNIP4, CALP KCHIP4
Cellular localization Membrane, Peripheral Membrane, Cytoplasm, Endoplasmic Reticulum
Research area Neuroscience
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID Q6PIL6
Product name Anti-KCNIP4 Antibody
Catalog No IGX-43915
Supplier’s Catalog No IGX-43915
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:20-1:200, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Kv channel-interacting protein 4 protein (1-250AA)
Specificity KCNIP4 antibody detects endogenous level of KCNIP4 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).