Anti-UBXN2B Antibody
Catalog No : IGX-43874
262.00€
188.00€
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| Description | Adapter protein required for Golgi and endoplasmic reticulum biogenesis (PMID:17141156). Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis (PMID:17141156). The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L (PMID:17141156). VCPIP1 is also required, but not its deubiquitinating activity (PMID:17141156). Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase (PMID:23649807). Also, regulates spindle orientation during mitosis (PMID:23649807). | ||
|---|---|---|---|
| Other names | UBX domain-containing protein 2B, NSFL1 cofactor p37, p97 cofactor p37, UBXN2B | ||
| Cellular localization | Cytoplasm, Cytoskeleton, Endoplasmic Reticulum, Golgi Apparatus, Nucleus | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q14CS0 | ||
| Product name | Anti-UBXN2B Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43874 | ||
| Supplier’s Catalog No | IGX-43874 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human UBX domain-containing protein 2B protein (2-250AA) | ||
| Specificity | UBXN2B antibody detects endogenous level of UBXN2B protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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