Anti-ABCB1 / ATP-binding cassette, sub-family B (MDR/TAP), member 11 Antibody
Catalog No : IGX-43861
262.00€
188.00€
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| Description | Translocates drugs and phospholipids across the membrane (PMID:8898203, PMID:2897240, PMID:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PMID:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PMID:2897240, PMID:9038218). | ||
|---|---|---|---|
| Other names | Multidrug resistance protein 1, EC 3.6.3.44, ATP-binding cassette sub-family B member 1, P-glycoprotein 1, CD antigen CD243, ABCB1, MDR1 PGY1 | ||
| Cellular localization | Membrane, Multi-Pass Membrane, Apical Membrane | ||
| Research area | Signal Transduction | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P08183 | ||
| Product name | Anti-ABCB1 / ATP-binding cassette, sub-family B (MDR/TAP), member 11 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43861 | ||
| Supplier’s Catalog No | IGX-43861 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Multidrug resistance protein 1 protein (236-297AA) | ||
| Specificity | ABCB1 antibody detects endogenous level of ABCB1 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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