Anti-TNFSF10 Antibody

Catalog No : IGX-43843
262.00€
188.00€

Shipping cost plus VAT not included , delivery in 7-14 business days

Description Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PMID:26457518, PMID:10549288). Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Other names Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, Protein TRAIL, CD antigen CD253, TNFSF10, APO2L TRAIL
Cellular localization Membrane, Single-Pass Type Ii Membrane, Secreted
Research area Cell Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P50591
Product name Anti-TNFSF10 Antibody
Catalog No IGX-43843
Supplier’s Catalog No IGX-43843
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:20-1:200, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Tumor necrosis factor ligand superfamily member 10 protein (39-281AA)
Specificity TNFSF10 antibody detects endogenous level of TNFSF10 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).