Anti-SLPI Antibody
Catalog No : IGX-43841
262.00€
188.00€
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| Description | Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G (PMID:3533531, PMID:3462719, PMID:2039600, PMID:2110563, PMID:10702419, PMID:24121345). Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS) . Plays a role in regulating the activation of NF-kappa-B and inflammatory responses (PMID:10702419, PMID:24352879). Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for normal resistance to infection by L.major. Required for normal wound healing, probably by preventing tissue damage by limiting protease activity . Together with ELANE, required for normal differentiation and proliferation of bone marrow myeloid cells (PMID:24352879). | ||
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| Other names | Antileukoproteinase, ALP, BLPI, HUSI-1, Mucus proteinase inhibitor, MPI, Protease inhibitor WAP4, Secretory leukocyte protease inhibitor, Seminal proteinase inhibitor, WAP four-disulfide core domain protein 4, SLPI, WAP4 WFDC4 | ||
| Cellular localization | Secreted | ||
| Research area | Immunology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P03973 | ||
| Product name | Anti-SLPI Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43841 | ||
| Supplier’s Catalog No | IGX-43841 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Antileukoproteinase protein (26-132AA) | ||
| Specificity | SLPI antibody detects endogenous level of SLPI protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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