Anti-SLC28A1 Antibody

Catalog No : IGX-43781
262.00€
188.00€

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Description Sodium-dependent and pyrimidine-selective transporter (PMID:21998139). Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine). Transports uridine, cytidine, thymidine, and nucleoside-derived drugs (PMID:21998139). Transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC). It may be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS). It has the following selective inhibition: adenosine, thymidine, cytidine, uridine >> guanosine, inosine.
Other names Sodium/nucleoside cotransporter 1, Concentrative nucleoside transporter 1, CNT 1, hCNT1, Na,+,/nucleoside cotransporter 1, Sodium-coupled nucleoside transporter 1, Solute carrier family 28 member 1, SLC28A1, CNT1
Cellular localization Membrane, Multi-Pass Membrane
Research area Cell Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID O00337
Product name Anti-SLC28A1 Antibody
Catalog No IGX-43781
Supplier’s Catalog No IGX-43781
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:20-1:200, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Sodium/nucleoside cotransporter 1 protein (1-80AA)
Specificity SLC28A1 antibody detects endogenous level of SLC28A1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).