Anti-RNF183 Antibody
Catalog No : IGX-43771
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Acts as a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins (PMID:29507230). Triggers apoptosis in response to prolonged ER stress by mediating the polyubiquitination and subsequent proteasomal degradation of BCL2L1 (PMID:29507230). May collaborate with FATE1 to restrain BIK protein levels thus regulating apoptotic signaling (PMID:26567849). | ||
|---|---|---|---|
| Other names | E3 ubiquitin-protein ligase RNF183, RNF183 | ||
| Cellular localization | Golgi Apparatus, Cis-Golgi Network Membrane, Lysosome Membrane, Endoplasmic Reticulum Membrane, Single-Pass Type Iv Membrane, Endoplasmic Reticulum | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q96D59 | ||
| Product name | Anti-RNF183 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43771 | ||
| Supplier’s Catalog No | IGX-43771 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC, IF | ||
| Recommended dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human E3 ubiquitin-protein ligase RNF183 protein (1-161AA) | ||
| Specificity | RNF183 antibody detects endogenous level of RNF183 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
Product Details
© 2020 Imugex All Rights Reserved