Anti-HNRNPL Antibody

Catalog No : IGX-43699
262.00€
188.00€

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Description Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements (PMID:11809897, PMID:22570490, PMID:24164894, PMID:25623890, PMID:26051023). Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts (PMID:2687284). Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter (PMID:11809897).
Other names Heterogeneous nuclear ribonucleoprotein L, hnRNP L, HNRNPL, HNRPL
Cellular localization Cytoplasm, Nucleus
Research area Cell Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID P14866
Product name Anti-HNRNPL Antibody
Catalog No IGX-43699
Supplier’s Catalog No IGX-43699
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC, IF
Recommended dilutions IHC: 1:20-1:200, IF: 1:50-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human Heterogeneous nuclear ribonucleoprotein L protein (89-335AA)
Specificity HNRNPL antibody detects endogenous level of HNRNPL protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).