Anti-MFNG Antibody
Catalog No : IGX-43508
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PMID:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 . | ||
|---|---|---|---|
| Other names | Beta-1,3-N-acetylglucosaminyltransferase manic fringe, EC 2.4.1.222, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, MFNG | ||
| Cellular localization | Golgi Apparatus Membrane, Single-Pass Type Ii Membrane | ||
| Research area | |||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O00587 | ||
| Product name | Anti-MFNG Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43508 | ||
| Supplier’s Catalog No | IGX-43508 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Beta-1,3-N-acetylglucosaminyltransferase manic fringe protein (28-321AA) | ||
| Specificity | MFNG antibody detects endogenous level of MFNG protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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