Anti-ABCD4 / ATP-binding cassette, sub-family D (ALD), member 4 Antibody
Catalog No : IGX-43506
262.00€
188.00€
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| Description | Lysosomal transporter that plays a role in the lysosomal release of vitamin B12 into the cytosol (PMID:22922874). Targeted by LMBRD1 lysosomal chaperone from the endoplasmic reticulum to the lysosomal membrane (PMID:27456980). Then forms a complex with lysosomal chaperone LMBRD1 and cytosolic MMACHC to transport cobalamin across the lysosomal membrane (PMID:25535791). | ||
|---|---|---|---|
| Other names | ATP-binding cassette sub-family D member 4, PMP70-related protein, P70R, Peroxisomal membrane protein 1-like, PXMP1-L, Peroxisomal membrane protein 69, PMP69, ABCD4, PXMP1L | ||
| Cellular localization | Endoplasmic Reticulum Membrane, Multi-Pass Membrane, Lysosome Membrane | ||
| Research area | Cell Biology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | O14678 | ||
| Product name | Anti-ABCD4 / ATP-binding cassette, sub-family D (ALD), member 4 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43506 | ||
| Supplier’s Catalog No | IGX-43506 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human ATP-binding cassette sub-family D member 4 protein (335-606AA) | ||
| Specificity | ABCD4 antibody detects endogenous level of ABCD4 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
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| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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