Anti-SOX10 Antibody
Catalog No : IGX-43504
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Transcription factor that plays a central role in developing and mature glia . Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination . Once induced, MYRF cooperates with SOX10 to implement the myelination program . Transcriptional activator of MITF, acting synergistically with PAX3 (PMID:21965087). Transcriptional activator of MBP, via binding to the gene promoter . | ||
|---|---|---|---|
| Other names | Transcription factor SOX-10, SOX10 | ||
| Cellular localization | Mitochondrion Outer Membrane, Peripheral Membrane, , Nucleus, Cytoplasm | ||
| Research area | Neuroscience | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P56693 | ||
| Product name | Anti-SOX10 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43504 | ||
| Supplier’s Catalog No | IGX-43504 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Peptide sequence from Human Transcription factor SOX-10 protein (49-68AA) | ||
| Specificity | SOX10 antibody detects endogenous level of SOX10 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | Concentration can vary between different batches. | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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