Anti-UBE2M Antibody
Catalog No : IGX-43495
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation. | ||
|---|---|---|---|
| Other names | NEDD8-conjugating enzyme Ubc12, EC 2.3.2.-, NEDD8 carrier protein, Ubiquitin-conjugating enzyme E2 M, UBE2M, UBC12 | ||
| Cellular localization | Cytosol, Nucleoplasm | ||
| Research area | Epigenetics & Nuclear Signaling | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P61081 | ||
| Product name | Anti-UBE2M Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43495 | ||
| Supplier’s Catalog No | IGX-43495 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Peptide sequence from Human NEDD8-conjugating enzyme Ubc12 protein (11-28AA) | ||
| Specificity | UBE2M antibody detects endogenous level of UBE2M protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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