Anti-LTN1 Antibody

Catalog No : IGX-43479
262.00€
188.00€

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Description E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PMID:23685075, PMID:25132172, PMID:25578875). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product .
Other names E3 ubiquitin-protein ligase listerin, EC 2.3.2.27, RING finger protein 160, RING-type E3 ubiquitin transferase listerin, Zinc finger protein 294, LTN1, C21orf10 C21orf98 KIAA0714 RNF160 ZNF294
Cellular localization Cytosol, Rqc Complex
Research area Cell Biology
Note This product is for research purpose only, not for use in diagnostics or as therapeutics.
Uniprot ID O94822
Product name Anti-LTN1 Antibody
Catalog No IGX-43479
Supplier’s Catalog No IGX-43479
Supplier ImuGeX
Host species Rabbit
Species reactivity Human
Applications ELISA, IHC
Recommended dilutions IHC: 1:20-1:200
Molecular weight N/A
Conjugate Unconjugated
Immunogen Recombinant Human E3 ubiquitin-protein ligase listerin protein (462-591AA)
Specificity LTN1 antibody detects endogenous level of LTN1 protein
Storage Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity.
Clonality Polyclonal
Isotype IgG
Clone ID N/A
Concentration 1 mg/mL
Storage buffer Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol.
Formulation Liquid
Purification This antibody is immunogen affinity purified.
Handling This product contains Proclin as preservative, please take appropriate care when handling this product.
Reactivity life 12 months when stored properly according to instructions (provided antibody remains sterile).