Anti-F12 Antibody
Catalog No : IGX-43413
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. | ||
|---|---|---|---|
| Other names | Coagulation factor XII, EC 3.4.21.38, Hageman factor, HAF, [Cleaved into: Coagulation factor XIIa heavy chain, Beta-factor XIIa part 1, Coagulation factor XIIa light chain, Beta-factor XIIa part 2,], F12 | ||
| Cellular localization | Secreted | ||
| Research area | Cardiovascular | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | P00748 | ||
| Product name | Anti-F12 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43413 | ||
| Supplier’s Catalog No | IGX-43413 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Coagulation factor XII protein (486-600AA) | ||
| Specificity | F12 antibody detects endogenous level of F12 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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