Anti-DEFB126 Antibody
Catalog No : IGX-43387
262.00€
188.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Description | Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte . In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation (PMID:19373462, PMID:23229569). | ||
|---|---|---|---|
| Other names | Beta-defensin 126, Beta-defensin 26, DEFB-26, Defensin, beta 126, Epididymal secretory protein 13.2, ESP13.2, HBD26, DEFB126, C20orf8 DEFB26 | ||
| Cellular localization | Secreted | ||
| Research area | Microbiology | ||
| Note | This product is for research purpose only, not for use in diagnostics or as therapeutics. | ||
| Uniprot ID | Q9BYW3 | ||
| Product name | Anti-DEFB126 Antibody | ||
|---|---|---|---|
| Catalog No | IGX-43387 | ||
| Supplier’s Catalog No | IGX-43387 | ||
| Supplier | ImuGeX | ||
| Host species | Rabbit | ||
| Species reactivity | Human | ||
| Applications | ELISA, IHC | ||
| Recommended dilutions | IHC: 1:20-1:200 | ||
| Molecular weight | N/A | ||
| Conjugate | Unconjugated | ||
| Immunogen | Recombinant Human Beta-defensin 126 protein (36-111AA) | ||
| Specificity | DEFB126 antibody detects endogenous level of DEFB126 protein | ||
| Storage | Store at +4°C for short term (1 week), for long term aliquote and store at -20°C or -80°C. Avoid repeated freeze and thaw cycles, with each freeze and thaw cycle an antibody can lose half of its binding activity. | ||
|---|---|---|---|
| Clonality | Polyclonal | ||
| Isotype | IgG | ||
| Clone ID | N/A | ||
| Concentration | 1 mg/mL | ||
| Storage buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. | ||
| Formulation | Liquid | ||
| Purification | This antibody is immunogen affinity purified. | ||
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. | ||
| Reactivity life | 12 months when stored properly according to instructions (provided antibody remains sterile). | ||
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